Search results for "living heart human model"

showing 2 items of 2 documents

Numerical simulation of transcatheter mitral valve replacement: The dynamic implication of LVOT obstruction in the valve-in-ring case.

2022

Transcatheter mitral valve replacement (TMVR) has been used for “off-label” treatment when annuloplasty band ring for mitral repair fails. However, the complex anatomy and function of the mitral valve may lead to fatal complications as a result of the left ventricular outflow tract (LVOT) obstruction in TMVR. We report the structural and hemodynamic response of LVOT obstruction resulting from TMVR with the Edwards SAPIEN 3 Ultra (S3) device. We modified the original Living Heart Human Model (LHHM) to account for a failed mitral valve with an annuloplasty band ring and simulated the cardiac beating condition in the setting of S3 device implantation. Findings demonstrated a high dynamic behav…

Heart Valve Prosthesis ImplantationHeart Defects CongenitalHistoryCardiac CatheterizationPolymers and PlasticsRehabilitationBiomedical EngineeringBiophysicsMitral Valve InsufficiencyFinite Element (FE) analysisIndustrial and Manufacturing EngineeringVentricular Outflow ObstructionTreatment OutcomeRisk FactorsComputational Fluid Dynamic (CFD)Living heart human modelHeart Valve ProsthesisHumansMitral ValveOrthopedics and Sports MedicineBusiness and International ManagementTranscatheter mitral valve replacementJournal of biomechanics
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Patient-Specific Analysis of Ascending Thoracic Aortic Aneurysm with the Living Heart Human Model

2021

In ascending thoracic aortic aneurysms (ATAAs), aneurysm kinematics are driven by ventricular traction occurring every heartbeat, increasing the stress level of dilated aortic wall. Aortic elongation due to heart motion and aortic length are emerging as potential indicators of adverse events in ATAAs

Technologymedicine.medical_specialtyAscending aortic aneurysm Cardiac mechanics Finite element analysis Living heart human modelliving heart human modelHeartbeatQH301-705.5Bioengineeringfinite element analysisThoracic aortic aneurysmArticlecardiac mechanicsAneurysmascending aortic aneurysmInternal medicinemedicinecardiovascular diseasesBiology (General)Computed tomography angiographymedicine.diagnostic_testbusiness.industryTBiomechanicsSettore ING-IND/34 - Bioingegneria IndustrialePatient specificmedicine.diseaseAortic wallcardiovascular systemCardiologybusinessCardiac mechanicsBioengineering
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